osteogenesis imperfecta



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Osteogenesis Imperfecta

History: infant who died shortly after birth

Osteogenesis Imperfecta: full body x-ray of a neonate demonstrates multiple rib fractures, right femur fracture and right forearm fractures (yellow arrows), to name a few.
Osteogenesis imperfecta (OI), also known as brittle bone disease, is a congenital bone disorder characterized by brittle bones that are prone to fracture. People with OI are born with defective connective tissue, or without the ability to make it, usually because of a deficiency of type I collagen.
On imaging, the following characteristic findings can be seen:….